Healthy, Radiant Skin is Achievable with TruRadiance
Objective: To evaluate the skin brightening and lightening efficacy of PhytoflORAL®
Protocol
A double blind placebo-controlled trial of PhytoflORAL® was conducted with 43 asian females aged between 20 to 40 years with phototype (Fitzpatrick) IV.
21 of them had received 1g of 100% PhytoflORAL® while 22 of them were assigned to take a placebo which is inactive.
Measurements were taken before consumption on Day 0 and after 42 days of usage.
Methods
Skin color was obtained using a tristimulus color analyzer measuring reflected color (Chromameter CR200, Minolta, Japan). The system uses high sensitivity photocells filtered to match CIE standard.
The system detects any deviation in the xenon’s light spectral distribution. The system provides data for the L* (Luminance), a* (red-green) and b* (blue-yellow) color distribution. The Individual Typological Angle (ITA˚) single-number skin tone index is calculated based on the L* and b* values, according to the formula: ITA° = [ArcTan((L*-50)/b*)] x 180 / . A higher ITA˚ value corresponds to lighter skin. The measurement was carried out in a defined area on each subject’s back. The same area was evaluated at D0 and D42.
Standardized photographic images were obtained with cross-polarized lighting (frontal angle), using the VISIA system (Canfield, USA).
Resulting data and percentage variations were submitted to the paired or unpaired t-test, or to the Wilcoxon test (*p<0.05).
Results
Evaluation of skin glow
p=0.08, *p<0.05
Subject age 22, skin tone at Day 0 (left) and at Day 42 (right)
Conclusion
PhytoflORAL® helps to brighten and lighten skin tone to achieve a look of healthy skin radiance.
Objective: To investigate the ability of PhytoflORAL® to provide skin photoprotection against UV rays
Protocol
22 Caucasian females were included in this trial, with ages from 20 to 40 years and phototype (Fitzpatrick) II.
Subjects received 1g of 100% PhytoflORAL® powder.
Measurements were carried out before consumption on D0 and after 42 and 84 days of usage.
Methods
The Minimal Erythemal Dose (MED) is the minimum dosage of UV radiation required to cause a detectable erythema 16 to 24hours after exposure. This dose will vary from subject to subject and is determined individually. The MED determination was carried out on the subjects’ back. Irradiation was carried out using a Multiport 601-300W Solar Light device, with a WG320 filter (1.25 mm). The radiation spectrum was 290 - 400 nm (UVA + UVB). Skin was exposed each time to a range of six UV doses, each on an 8-mm diameter area. Erythema was read on the day following each irradiation. The lowest dose producing a clearly contoured erythema is the MED.
Grading of cutaneous dryness, roughness, suppleness, evenness and texture was carried out by trained clinicians, according to a five-point scale for each parameter (from perfect to severely flawed, for each parameter – such that a decrease in grades reflects an improvement in skin condition). Grading was carried out on the face.
Study participants answered a self-assessment questionnaire at each study time point, including parameters of skin radiance, evenness, hydration, suppleness, elasticity, visible skin health and overall beauty. Each parameter was graded on a 10-point scale, from severely flawed to perfect such that an increase in scores indicated an improvement in skin condition.
Resulting data and percentage variations were submitted to the paired or unpaired t-test, or to the Wilcoxon test (*p<0.05).
Results
Although the use of PhytoflORAL® did not affect the subject’s MED after 42 days, a significant MED increase (10% vs. D0) was recorded at 84 days, attesting to its photoprotective effect.
Evaluation of photoprotective effect
Minimum Erythemal Dose (MED) variation (% vs. D0)**p<0.01
Clinical grading shows significant improvements in skin characteristics of dryness, roughness, suppleness, evenness and texture. These effects also seem to build over time and are stronger at D84 than at D42.
Evaluation of skin quality (clinical grading)
Clinical scoring variation (% vs.D0) p<0.01, *p<0.001
Participant self-evaluation shows significant improvements in skin parameters including skin radiance, evenness, hydration, suppleness, elasticity, visible skin health and overall beauty. Here also, the effect appears to build over time and is stronger at D84 than at D42.
Evaluation of skin quality (self-assessment)
Self scoring variation (% vs.D0)
Conclusion
PhytoflORAL® helps to brighten and lighten skin tone to achieve a look of healthy skin radiance.
Reference:
PhytoflORAL® by Lucas Meyer Cosmetics, International Flavors & Fragrances Inc. IFF®